Educational Articles
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Moxidectin is an avermectin antiparasitic that is used to prevent heartworms and treat intestinal parasites. Imidacloprid treats and prevents fleas. These two drugs are combined in one topical product for use in cats, dogs, and ferrets. Use as directed. Side effects are uncommon and usually short-lived, however, if you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.
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Moxidectin + sarolaner + pyrantel is a heartworm disease preventive for dogs that also treats and prevents internal parasites (hookworms and roundworms) and kills fleas and ticks. This medication is given by mouth as a flavored chew tablet. At regular doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of moxidectin + sarolaner + pyrantel use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.
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Moxidectin injectable is used in dogs to prevent heartworm disease and treat existing hookworm infections. It comes as an injectable medication which must be given by your veterinarian or a trained veterinary staff member, and provides protection for several months. Dogs should be tested for heartworm disease to ensure they are negative prior to using this medication.
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Moxidectin topical is applied to the skin and is commonly used to prevent heartworms and to treat topical and intestinal parasites. It has also been used off-label to treat adult heartworms. Side effects are uncommon but may include lethargy, vomiting, uncoordinated walking, anorexia, diarrhea, and itching. It should not be used in sick, debilitated, or underweight animals.
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Pain research has advanced suggesting that a more appropriate choice for managing the chronic pain of OA is multi-modal therapy. Non-steroidal anti-inflammatory drugs are just one of the options leveraged for multi-modal OA management. These include joint supplements, nutraceuticals, nutrition, adjunctive medicines, physical medicine, and changes to the home environment. Every multi-modal treatment plan is tailored to meet the needs of the individual patient and then adjusted as treatment progresses. Once a full multi-modal pain management plan is in place, your veterinarian may be able to lower the dose of NSAID to minimize the risk of an adverse event, and to reserve a full therapeutic dose for any acute inflammatory pain event.
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Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.
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Mupirocin otic, also known as pseudomonic acid A, is an antibiotic used in the treatment of ear infections. It is used “off label” or “extra label” to treat ear infections in animals. Mupirocin comes in ointment or liquid drop suspension forms that may be specially compounded.
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Mupirocin topical, also known as pseudomonic acid A (brand names Muricin, Bactroban, Centany), is an antibiotic used to treat skin infections. It is labeled for use in dogs to treat skin infections caused by susceptible strains of Staphlococcus and other gram-positive bacteria. It is used “off label” or “extra label” to treat skin infections in other species and acne in cats. Mupirocin comes in cream or ointment form.
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Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury or strain caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in cats and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.
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Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury, or strain, caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in dogs and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.
